Co-treatment of TBI and Post-Traumatic Stress Disorder
| Treatment | Examples | Rationale |
|---|---|---|
| SSRI antidepressants (2, 18, 26) | Sertraline, paroxetine, fluoxetine, citalopram, fluvoxamine | Considered first-line therapy for both PTSD and depression |
| Other antidepressants (18) | Bupropion, nefazodone, trazodone, venlafaxine, phenelzine | Considered second-line therapy for PTSD and depression |
| Sympatholytics (18) | Prazocin | Block autonomic hyperarousal, treat nightmares |
| Other psychotropic drugs (18) | Carbamazepine, duloxetine | For irritability, flash anger, and violent outbursts |
| Anticonvulsants (2) | Valproate | migraines and behavioral symptoms |
| Atypical antipsychotics (18) | Quetiapine | For insomnia |
| Stimulants (2) | Methylphenidate, dextroamphetamine | for attention problems or information processing |