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Lights on for Low Oxygen: A Noninvasive Mouse Model Useful for Sensing Oxygen Deficiency
Table 1.
(Patho-) Physiological Situations Associated with Increased HIF-1 Activity
| HIF-1 Beneficial | HIF-1 Detrimental |
|---|---|
| Organ transplants | Tumor growth |
| Cerebral stroke | Malignancy |
| Cardiac infarction | Diabetic retinopathy |
| Immune response | Rheumatoid arthritis |
| Wound healing |
